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AT13387 Onalespib

AT13387 Onalespib 912999-49-6
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Chemical Information
Product name:AT13387 Onalespib Purity:98% min
CAS NO:912999-49-6 Solubility:DMSO : ≥ 33 mg/mL (80.58 mM)
Molecular Formula:C24H31N3O3 Package:Package according to customer requirements
Molecular Weight:409.521 Storage:Store at -20℃
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Onalespib, also known as AT13387 , is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor AT13387 selectively binds to Hsp90, thereby inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. Hsp90, a chaperone protein upregulated in a variety of tumor cells, regulates the folding, stability and degradation of many oncogenic signaling proteins.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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