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H-89 2HCl

H-89 2HCl 130964-39-5
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Chemical Information
Product name:H-89 2HCl Purity:98% min
CAS NO:130964-39-5 Solubility:DMSO: ≥ 29 mg/mL
Molecular Formula:C20H24BrCl2N3O3S Package:Package according to customer requirements
Molecular Weight:537.298 Storage:Store at -20℃
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Remarks

H-89 is a specific adenylyl cyclase inhibitor (DDA) and a cyclic AMP-dependent protein kinase inhibitor. H-89 blocks the action of equine growth hormone on in vitro maturation of equine oocytes. H-89 decreases the gain of excitation-contraction coupling and attenuates calcium sparks in the absence of beta-adrenergic stimulation. H-89 potentiates adipogenesis in 3T3-L1 cells by activating insulin signaling independently of protein kinase A.

H-89 dihydrochloride is a potent inhibitor of protein kinase A (PKA) with an IC50 of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase.

 

 

 

S6 Kinase Inhibitors Related Prodcuts:

BI-D1870; AT7867; H-89; Staurosporine; Pluripotin; LY-2584702; AT13148; Bosutinib; PF-4708671

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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