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GDC-0994 Ravoxertinib

GDC-0994 Ravoxertinib 1453848-26-4
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Chemical Information
Product name:GDC-0994 Ravoxertinib Purity:98% min
CAS NO:1453848-26-4 Solubility:DMSO : ≥ 35 mg/mL (79.39 mM)
Molecular Formula:C21H18ClFN6O2 Package:Package according to customer requirements
Molecular Weight:440.858 Storage:Store at -20℃
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Remarks

Ravoxertinib also known as GDC-0994 and RG7842, is an orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic activity. Upon oral administration, GDC-0994 inhibits both ERK phosphorylation and activation of ERK-mediated signal transduction pathways. This prevents ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival.

 

 

 

ERK Inhibitors Related Products:

BIX02189; Resveratrol; SCH772984; Pluripotin; VX-11e; DEL-22379; Ulixertinib; XMD8-92; Bosutinib; ERK5-IN-1; ONC-201; AZD-0364

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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