Baloxavir (Baloxavir acid, S-033447) is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor with an IC50 of 2.5 nM. BXA inhibits viral RNA transcription via selective inhibition of CEN activity.
Synonyms:
(12aR)-12-[(11S)-7,8-Difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-6,8-dioxo-3,4,6,8,12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-ol;
Properties:
Boiling point: 644.7±65.0 °C(Predicted)
density: 1.63±0.1 g/cm3(Predicted)
pka: 4.50±1.00(Predicted)
Antiviral Inhibitors Related Products:
Vadimezan; Geldanamycin; UNC0638; U0126-EtOH; Tenofovir; Tubacin; NGI-1(ML414); Emricasan; Remdesivir; Baloxavir marboxil; Famciclovir; Epigoitrin; Ribavirin