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Product :

U0126-EtOH

U0126-EtOH 1173097-76-1
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Chemical Information
Product name:U0126-EtOH Purity:98% min
CAS NO:1173097-76-1 Solubility:DMSO : ≥ 49 mg/mL (114.87 mM)
Molecular Formula:C20H22N6OS2 Package:Package according to customer requirements
Molecular Weight:426.558 Storage:Store at -20℃
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Remarks

U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059. This inhibition of MEK1/2 is noncompetitive with ERK and ATP.

 

Synonyms:

AZD8330;

ARRY-704;

2-(2-fluoro-4-iodophenylamino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide;

UNII-G4990BOZ66;

 

 

 

MEK Inhibitor Related Products:

Selumetinib; Mirdametinib (PD0325901); Trametinib; PD184352 (CI-1040); PD98059; BIX02189; Pimasertib; BIX02188; TAK-733; Binimetinib (MEK162); SL327; Refametinib; GDC-0623; RO5126766 (CH5126766); Cobimetinib; APS-2-79 hydrochloride; AZD8330

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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