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PD0325901

PD0325901 391210-10-9
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Chemical Information
Product name:PD0325901 Purity:98% min
CAS NO:391210-10-9 Solubility:DMSO: ≥ 56 mg/mL
Molecular Formula:C16H14F3IN2O4 Package:Package according to customer requirements
Molecular Weight:482.193 Storage:Store at -20℃
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Remarks
PD-0325901 is a potent bioavailable and selective MEK inhibitor, which targets mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity. MEK inhibitor PD325901, a derivative of MEK inhibitor CI-1040, selectively binds to and inhibits MEK, which may result in the inhibition of the phosphorylation and activation of MAPK/ERK and the inhibition of tumor cell proliferation. The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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