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BAY 869766 Refametinib

BAY 869766 Refametinib 923032-37-5
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Chemical Information
Product name:BAY 869766 Refametinib Purity:98% min
CAS NO:923032-37-5 Solubility:DMSO : ≥ 31 mg/mL (54.16 mM)
Molecular Formula:C19H20F3IN2O5S Package:Package according to customer requirements
Molecular Weight:572.337 Storage:Store at -20℃
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Remarks
Refametinib, also known as RDEA119, BAY 86-9766, is an orally bioavailable selective MEK inhibitor with potential antineoplastic activity. MEK inhibitor RDEA119 specifically inhibits mitogen-activated protein kinase kinase 1 (MAP2K1 or MAPK/ERK kinase 1), resulting in inhibition of growth factor-mediated cell signaling and tumor cell proliferation. MEK, a dual specificity threonine/tyrosine kinase, is a key component of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth; constitutive activation of this pathway has been implicated in many cancers.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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