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Product :

Tubacin

Tubacin 537049-40-4
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Chemical Information
Product name:Tubacin Purity:98% min
CAS NO:537049-40-4 Solubility:10 mM in DMSO
Molecular Formula:C41H43N3O7S Package:Package according to customer requirements
Molecular Weight:721.861 Storage:Store at -20℃
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Remarks

Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM. The IC50 for other HDACs is 1000-fold higher, making tubacin both more selective and more potent than Tubastatin A, which also inhibits HDAC8. Tubacin inhibits alpha-tubulin deacetylation in mammalian cells. Unlike trichostatin A (TSA), which is a broad spectrum HDAC inhibitor, tubacin is specific for the tubulin deacetylase activity of HDAC6.


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