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SCH-417690 Vicriviroc

SCH-417690 Vicriviroc 306296-47-9
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Chemical Information
Product name:SCH-417690 Vicriviroc Purity:98% min
CAS NO:306296-47-9 Solubility:DMSO : 50 mg/mL (76.96 mM)
Molecular Formula:C28H38F3N5O2 Package:Package according to customer requirements
Molecular Weight:533.629 Storage:Store at -20℃
Quality control
Vicriviroc, also known as SCH 417690 and SCH-D, is a potent, orally active and selective CCR5 entry inhibitor of HIV-1. Vicriviroc is effective at nanomolar concentrations, it can be administered once daily. Vicriviroc binds to a small hydrophobic pocket between the transmembrane helices near the extracellular surface of the CCR5 receptor. Binding to this pocket induces a conformational change of the extracellular segment of CCR5 and prevents binding of gp120 to the target cell, consequently preventing the virus from entering the target cell at all.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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