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Vicriviroc Malate

Vicriviroc Malate 541503-81-5
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Chemical Information
Product name:Vicriviroc Malate Purity:98% min
CAS NO:541503-81-5 Solubility:DMSO : 50 mg/mL (76.96 mM)
Molecular Formula:667.716 Package:Package according to customer requirements
Molecular Weight:667.716 Storage:Store at -20℃
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Remarks
Vicriviroc, also known as SCH 417690 and SCH-D, is a potent, orally active and selective CCR5 entry inhibitor of HIV-1. Vicriviroc is effective at nanomolar concentrations, it can be administered once daily. Vicriviroc binds to a small hydrophobic pocket between the transmembrane helices near the extracellular surface of the CCR5 receptor. Binding to this pocket induces a conformational change of the extracellular segment of CCR5 and prevents binding of gp120 to the target cell, consequently preventing the virus from entering the target cell at all.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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