AEBSF is a specific irreversible serine protease inhibitor. AEBSF inhibits the rat embryo implantation in vivo and interferes with cell adhesion in vitro. Both AEBSF and PMSF are sulfonyl fluorides and are sulfonylating agents. Sulfonyl fluorides act by reacting with the hydroxy group of the active site serine residue to form a sulfonyl enzyme derivative. This derivative may be stable for long periods of time except at high pH.
AEBSF hydrochloride is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin.
Serine Protease Inhibitors Related Products:
Aprotinin; Alvelestat; Leupeptin hemisulfate; Nafamostat mesylate; Nafamostat; PMSF