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Product :

Alvelestat (AZD9688)

Alvelestat (AZD9688) 848141-11-7
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Chemical Information
Product name:Alvelestat (AZD9688) Purity:98% min
CAS NO:848141-11-7 Solubility:DMSO : ≥ 33 mg/mL (60.49 mM)
Molecular Formula:C25H22F3N5O4S Package:Package according to customer requirements
Molecular Weight:545.533 Storage:Store at -20℃
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Remarks

Avelestat, also known as AZD9668 and MPH-966, is a novel, oral inhibitor of neutrophil elastase (NE), an enzyme implicated in the signs, symptoms, and disease progression in NE-driven respiratory diseases such as bronchiectasis and chronic obstructive pulmonary disease via its role in the inflammatory process, mucus overproduction, and lung tissue damage. In cell-based assays, AZD9668 inhibited plasma NE activity in zymosan-stimulated whole blood. AZD9668 has the potential to reduce lung inflammation and the associated structural and functional changes in human diseases.

 

 

 

Serine Protease Inhibitors Related Products:

Aprotinin; Leupeptin hemisulfate; Nafamostat mesylate; Nafamostat; PMSF; AEBSF hydrochloride 

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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