AR-A014418 , also known as SN 4521, is a labeled Glycogen Synthase Kinase 3β (GSK-3β) inhibitor. AR-A014418 suppresses pancreatic cancer cell growth via inhibition of GSK-3-mediated Notch1 expression. AR-A014418 decreases neuropathic pain in mice: evidence for the mechanisms of action. AR-A014418 and B6B3O prevent human immunodeficiency virus-mediated neurotoxicity in primary human neurons.
GSK-3 Inhibitors Related Prodcuts:
TWS119; CHIR-99021; TDZD-8; 2-D08; BIO-Acetoxime; 5-Bromoindole; CP21R7 (CP21); SB-216763