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MDV3100 Enzalutamide

MDV3100 Enzalutamide 915087-33-1
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Chemical Information
Product name:MDV3100 Enzalutamide Purity:98% min
CAS NO:915087-33-1 Solubility:DMSO : ≥ 50 mg/mL (107.66 mM)
Molecular Formula:C21H16F4N4O2S Package:Package according to customer requirements
Molecular Weight:464.436 Storage:Store at -20℃
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Enzalutamide, also known as MDV3100, is an orally bioavailable, organic, non-steroidal small molecule targeting the androgen receptor (AR) with potential antineoplastic activity. Through a mechanism that is reported to be different from other approved AR antagonists, selective androgen receptor modulator MDV3100 inhibits the activity of prostate cancer cell ARs, which may result in a reduction in prostate cancer cell proliferation and, correspondingly, a reduction in the serum prostate specific antigen (PSA) level. In August 2012, the United States (U.S.) Food and Drug Administration (FDA) approved enzalutamide for the treatment of castration-resistant prostate cancer.

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