RU 58841

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Chemical Information

Product name：RU 58841	Purity：98% min
CAS NO：154992-24-2	Solubility：DMSO : ≥ 100 mg/mL (270.75 mM)
Molecular Formula：C₁₇H₁₈F₃N₃O₃	Package：Package according to customer requirements.
Molecular Weight：858.711	Storage：Store at -20℃

Quality control

COA

Remarks

RU-58841 is a new specific topical antiandrogen: a candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism. The potent localized inhibition of sebaceous glands by RU 58841 demonstrates the excellent potential of this compound as a topical drug for the treatment of acne and other androgen-mediated disorders.

Properties:

Density: 1.39

Boiling Point: 493.6ºC at 760 mmHg

Flash Point: 252.3ºC

Refractive Index: 1.559

Vapor Pressure: 1.47E-10mmHg at 25°C

Androgen Receptor Inhibitors Related Products:

Chlormadinone acetate; Bicalutamide; Apalutamide; Galeterone; Cyproterone acetate; AZD-3514; Spironolactone; ARV-110; Darolutamide; Megestrol Acetate; Clascoterone ; Enzalutamide

References

[1]. A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice By De Brouwer, B.; Tetelin, C.; Leroy, T.; Bonfils, A.; Van Neste, D. .From Briti

[2]. Münster U, Nakamura C, Haberland A, Jores K, Mehnert W, Rummel S, Schaller M, Korting HC, Zouboulis ChC, Blume-Peytavi U, Sch?fer-Korting M.RU 58841-myristate--prodrug development for topical treatment of acne and androgenetic alopecia.Pharmazie. 2005 Jan