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XL147 PI3K inhibitor X

XL147 PI3K inhibitor X 956958-53-5
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Chemical Information
Product name:XL147 PI3K inhibitor X Purity:98% min
CAS NO:956958-53-5 Solubility:10 mM in DMSO
Molecular Formula:C21H16N6O2S2 Package:Package according to customer requirements
Molecular Weight:448.521 Storage:Store at -20℃
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XL147-II is an ATP-competitive inhibitor of class I PI3K isoforms. It acts by abrogating Akt and S6 phosphorylation in HER2+ cells and also inducing the expression and phosphorylation of HER3 and other RTKs.
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