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GDC-0941 Pictilisib

GDC-0941 Pictilisib 957054-30-7
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Chemical Information
Product name:GDC-0941 Pictilisib Purity:98% min
CAS NO:957054-30-7 Solubility:DMSO: ≥ 29 mg/mL
Molecular Formula:C23H27N7O3S2 Package:Package according to customer requirements
Molecular Weight:513.636 Storage:Store at -20℃
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Remarks
Pictilisib, also known as Pictrelisib, GDC-0941, RG7321 and GNE0941 , is an orally bioavailable, and is a potent small-molecule thieno[3,2-d]pyrimidine inhibitor of the class I phosphatidylinositol 3 kinase (PI3K) isoforms p100alpha and p100delta with potential antineoplastic activity. PI3K inhibitor GDC-0941 selectively binds to PI3K isoforms in an ATP-competitive manner, inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway; inhibition of tumor cell growth, motility and survival in susceptible tumor cell populations may result.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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