SR 33557 Fantofarone

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Chemical Information

Product name：SR 33557 Fantofarone	Purity：98% min
CAS NO：114432-13-2	Solubility：DMSO : 150 mg/mL (272.38 mM)
Molecular Formula：C₃₁H₃₈N₂O₅S	Package：Package according to customer requirements
Molecular Weight：550.709	Storage：Store at -20℃

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Remarks

Fantofarone, also known as SR 33557, is a highly potent calcium channel antagonist representative of a new class of slow channel blockers. Fantofarone can significantly modify cardiac function and in particular, decrease MO2C consumption during periods of elevated heart rate. Fantofarone is able to induce submaximal peripheral vasodilating effects at doses that are devoid of any clinically significant cardiac effect.

Calcium Channel Related Products:

Manidipine 2HCl; Felodipine; Nisoldipine; Fasudil HCl; Cilnidipine; Dronedarone HCl; Clevidipine Butyrate; Efonidipine; Amlodipine; ISX-9 (Isoxazole 9); Gabapentin; MRS 1845; Suvecaltamide (MK-8998); Ziconotide; Catharanthine Tartrate ; Bepridil hydrochloride

References

[1]. Adovelande J, et al. Synergy between two calcium channel blockers, verapamil and fantofarone (SR33557), in reversing chloroquine resistance in Plasmodium falciparum. Biochem Pharmacol. 1998 Feb 15;55(4):433-40.

[2]. Dongay B, et al. Effect of fantofarone, a new Ca2+ channel antagonist, on angioplasty-induced vasospasm in an atherosclerotic rabbit model. Biochem Pharmacol. 1998 Jun 15;55(12):2047-50.