Cilnidipine

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Chemical Information

Product name：Cilnidipine	Purity：98% min
CAS NO：132203-70-4	Solubility：DMSO : ≥ 100 mg/mL (203.04 mM)
Molecular Formula：C₂₇H₂₈N₂O₇	Package：Package according to customer requirements
Molecular Weight：492.52	Storage：Store at -20℃

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Remarks

Cilnidipine, also known as FRC-8653, is a calcium channel blocker. Cilnidipine is the novel calcium antagonist accompanied with L-type and N-type calcium channel blocking function. It was approved in 1995. Compared with other calcium antagonists, cilnidipine can act on the N-type calcium channel that existing sympathetic nerve end besides acting on L-type calcium channel that similar to most of the calcium antagonists.

Properties:
Appearance & Physical State: yellow crystalline solid
Density: 1.24g/cm3
Melting Point: 97-99ºC
Boiling Point: 652.6ºC at 760mmHg
Flash Point: 348.5ºC
Refractive Index: 1.581

Calcium Channel Inhibitors Related Products:

Manidipine 2HCl; Felodipine; Nisoldipine; Fasudil HCl; Dronedarone HCl; Clevidipine Butyrate; Efonidipine; Amlodipine; ISX-9 (Isoxazole 9); Gabapentin; MRS 1845; Fantofarone; Suvecaltamide (MK-8998); Ziconotide; Catharanthine Tartrate ; Bepridil hydrochloride

References

[1]. Masuda T, Ogura MN, Moriya T, et al. Beneficial effects of L- and N-type calcium channel blocker on glucose and lipid metabolism and renal function in patients with hypertension and type II diabetes mellitus. Cardiovasc Ther. 2011 Feb;29(1):46-53. doi: 10

[2]. Morimoto S, Yano Y, Maki K, Iwasaka T. Renal and vascular protective effects of cilnidipine in patients with essential hypertension. J Hypertens. 2007 Oct;25(10):2178-83.