Suvecaltamide (MK-8998)

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Chemical Information

Product name：Suvecaltamide (MK-8998)	Purity：98% min
CAS NO：953778-58-0	Solubility：DMSO : ≥ 100 mg/mL (262.88 mM)
Molecular Formula：C₂₀H₂₃F₃N₂O₂	Package：Package according to customer requirements
Molecular Weight：380.404	Storage：Store at -20℃

Quality control

Remarks

MK-8998 is a T type calcium channel antagonist potentially for the treatment of schizophrenia. MK-8998 was not effective in treating acutely psychotic inpatients with schizophrenia, as measured by PANSS score at week 4.

Chemical Properties:

Boiling point: 510.3±50.0 °C(Predicted)

density: 1.178±0.06 g/cm3(Predicted)

pka: 14.27±0.46(Predicted)

Calcium Channel Related Products:

Manidipine 2HCl; Felodipine; Nisoldipine; Fasudil HCl; Cilnidipine; Dronedarone HCl; Clevidipine Butyrate; Efonidipine; Amlodipine; ISX-9 (Isoxazole 9); Gabapentin; MRS 1845; Fantofarone; Ziconotide; Catharanthine Tartrate ; Bepridil hydrochloride

References

[1]. Egan MF, et al. Randomized controlled study of the T-type calcium channel antagonist MK-8998 for the treatment of acute psychosis in patients with schizophrenia. Hum Psychopharmacol. 2013 Mar;28(2):124-33.