ISX-9 Isoxazole 9
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|Product name：ISX-9 Isoxazole 9
||Solubility：DMSO : ≥ 37 mg/mL (157.94 mM)
||Package：Package according to customer requirements
||Storage：Store at -20℃
ISX-9 is a neurogenic agent. Isx-9 promotes neurogenesis in vivo, enhancing the proliferation and differentiation of hippocampal subgranular zone (SGZ) neuroblasts, and the dendritic arborization of adult-generated dentate gyrus neurons. Isx-9 also improves hippocampal function, enhancing memory in the Morris water maze. Notably, Isx-9 enhances neurogenesis and memory without detectable increases in cellular or animal activity or vascularization. Isx-9 enhances hippocampal neurogenesis and memory in vivo, and its effects are reliant on Mef2, revealing a novel cell-intrinsic molecular pathway regulating adult neurogenesis.