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AG-18 Tyrphostin A23

AG-18 Tyrphostin A23 118409-57-7
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Chemical Information
Product name:AG-18 Tyrphostin A23 Purity:98% min
CAS NO:118409-57-7 Solubility:DMSO : ≥ 50 mg/mL (268.57 mM)
Molecular Formula:C10H6N2O2 Package:Package according to customer requirements
Molecular Weight:186.167 Storage:Store at -20℃
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AG-18, also known as RG-50810; RG-50858; TX 825; Tyrphostin A23; Tyrphostin AG-18. AG-18 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 35 µM in the human epidermoid carcinoma cell line A431. AG-18 inhibits internalization of the transferrin receptor by perturbing the interaction between tyrosine motifs and the medium chain subunit of the AP-2 adaptor complex.

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