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AM095 free acid

AM095 free acid 1228690-36-5
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Chemical Information
Product name:AM095 free acid Purity:99% min
CAS NO:1228690-36-5 Solubility:DMSO : 67.3 mg/mL (147.43 mM)
Molecular Formula:C27H24N2O5 Package:Package according to customer requirements
Molecular Weight:456.49 Storage:Store at -20℃
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Remarks

AM095 is a potent LPA1 receptor antagonist because it inhibited GTPγS binding to Chinese hamster ovary (CHO) cell membranes overexpressing recombinant human or mouse LPA1 with IC50 values of 0.98 and 0.73 μM, respectively, and exhibited no LPA1 agonism. Lysophosphatidic acid (LPA) is a bioactive phospholipid that signals through a family of at least six G protein-coupled receptors designated LPA1-6. LPA type 1 receptor (LPA1) exhibits widespread tissue distribution and regulates a variety of physiological and pathological cellular functions.

 

 

 

LPL Receptor Related Products:

Ki16425; Ki16198; Fingolimod hydrochloride; Siponimod; Ozanimod; CYM5520; JTE-013; Ponesimod; Etrasimod; AM966; CYM50308; NIBR-0213; VPC-23019; ONO-7300243

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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