Siponimod, also known as BAF-312, is a a potent and orally selective S1P Receptor Modulator with EC50 value of 0.39nM for S1P1 receptors and 0.98nM for S1P5 receptors, respectively. Development of sphingosine-1-phosphate receptor 1 (S1P1) modulators to dampen inflammation and its sequelae is becoming increasingly promising for treating medical conditions characterized by significant immunopathology.
Properties:
Boiling point: 602.0±65.0 °C(Predicted)
density: 1.24±0.1 g/cm3(Predicted)
pka: 2.69±0.20(Predicted)
LPL Receptor Related Products:
Ki16425; Ki16198; AM095; Fingolimod hydrochloride; Ozanimod; CYM5520; JTE-013; Ponesimod; Etrasimod; AM966; CYM50308; NIBR-0213; VPC-23019; ONO-7300243