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CGS-21680 HCl

CGS-21680 HCl 124182-57-6
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Chemical Information
Product name:CGS-21680 HCl Purity:98% min
CAS NO:124182-57-6 Solubility:DMSO : ≥ 20 mg/mL (37.31 mM)
Molecular Formula:C23H30ClN7O6 Package:Package according to customer requirements
Molecular Weight:535.981 Storage:Store at -20℃
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Remarks

CGS-21680 is a specific adenosine A2A subtype receptor agonist. It is soluble up to 3.4 mg/mL in DMSO and 20 mg/mL in 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin. The chemical is currently used by researchers interested in studying neuronal transmission with a high-affinity, subtype specific analogue for adenosine. This includes research in respiration where it is believed that A2A receptors are involved in rhythm generation in the pre-Bötzinger complex. The drug is not currently approved for use in a therapeutic capacity.

CGS 21680 HCl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor.

 

 

 

 

Adenosine Receptor Related Products:

ZM241385; Preladenant; Reversine; SCH-58261; Istradefylline; Regadenoson; CGS-15943; Tozadenant; Adenosine amine congener (ADAC); CGS-21680; Vipadenant

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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