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(-)-Corey lactone diol

(-)-Corey lactone diol 32233-40-2
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Chemical Information
Product name:(-)-Corey lactone diol Purity:99%min
CAS NO:32233-40-2 Solubility:Soluble in DMSO
Molecular Formula:C8H12O4 Package:Packaging according to customer requirements
Molecular Weight:172.18 Storage:Store at -20℃
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Corey aldehyde is a versatile, hydroxy-lactone intermediate for the synthesis of prostaglandins and prostaglandin analogs. Prostaglandin derivatives with modifications in the α chain, the ω chain, or both, are readily accessible from this general intermediate.1 (−)-Corey lactone diol is simply the reduced version of Corey aldehyde, with alcohol groups at both C-11 and C-13. This allows the introduction of ω chain constituents via alternate chemistries, such as nucleophilic displacements.
1. Bindra, J.S. and Bindra, R. Prostaglandin Synthesis. (1977).
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