UK-20349 Tioconazole

Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast. It is marketed under the brand names Trosyd and Gyno-Trosyd (Pfizer). Tioconazole ointments serve to treat women's vaginal yeast infections. Tioconazole topical (skin) preparations are also available for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus".

Properties
Density: 1.44g/cm3
Boiling Point: 534.5ºC at 760 mmHg
Flash Point: 277ºC
Refractive Index: 1.654

Fungal Inhibitors Related Products:

Miconazole nitrate; AN2718; Terbinafine HCl; Liranaftate; Fenticonazole Nitrate; Amorolfine HCl; Butoconazole nitrate; Tavaborole; Cicloheximide; Luliconazole; Efinaconazole; Isavuconazole; Micafungin sodium; Micafungin; Butenafine hydrochloride

1: Rosato A, Piarulli M, Schiavone BI, Montagna MT, Caggiano G, Muraglia M, Carone A, Franchini C, Corbo F. In vitro synergy testing of anidulafungin with fluconazole, tioconazole, 5-flucytosine and amphotericin B against some Candida spp. Med Chem. 2012 Jul;8(4):690-8. PubMed PMID: 22530916.

2: Grudzień M, Gajewska A, Pluciński F, Mazurek AP. Molecular properties relevant to bioavailability of tioconazole and its derivatives. Acta Pol Pharm. 2008 Nov-Dec;65(6):757-8. PubMed PMID: 19172861.

3: Grudzień M, Krakowiak N, Pluciński F, Mazurek AP. Molecular properties of oxyconazole and tioconazole as the criteria for their bioavailability estimation. Acta Pol Pharm. 2008 Jan-Feb;65(1):123-4. PubMed PMID: 18536184.