Amorolfine hydrochloride

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Chemical Information

Product name：Amorolfine hydrochloride	Purity：98% min
CAS NO：78613-38-4	Solubility：DMSO : 12.5 mg/mL (35.31 mM)
Molecular Formula：C₂₁H₃₆ClNO	Package：Package according to customer requirements
Molecular Weight：362.46	Storage：Store at -20℃

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Remarks

Amorolfine HCl is a 14-alpha demethylase inhibitor that inhibits ergosterol synthesis and fungal cell wall formation. In also increases release for prostaglandin D2 metabolites and inhibits production of thymic stromal lymphopoietin in dermatitis models.

Properties:
Appearance & Physical State: white powder
Density: 1.234
Boiling Point: 407.1ºC at 760 mmHg

Fungal Inhibitors Related Products:

Miconazole nitrate; AN2718; Terbinafine HCl; Liranaftate; Fenticonazole Nitrate; Tioconazole; Butoconazole nitrate; Tavaborole; Cicloheximide; Luliconazole; Efinaconazole; Isavuconazole; Micafungin sodium; Micafungin ; Butenafine hydrochloride

References

[1]. Polak, A., Preclinical data and mode of action of amorolfine. Dermatology, 1992. 184 Suppl 1: p. 3-7.

[2]. Richardson, M.D., G.S. Shankland, and C.A. Gray, Effect of amorolfine (Ro 14-4767/002) on in vitro phagocytosis and intracellular killing of Candida albicans by human neutrophils. Mycoses, 1989. 32(5): p. 245-9.