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BMS-863233

BMS-863233 1169562-71-3
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Chemical Information
Product name:BMS-863233 Purity:98% min
CAS NO:1169562-71-3 Solubility:Soluble in DMSO
Molecular Formula:C14H13Cl2N3O2 Package:Package according to customer requirements
Molecular Weight:289.72 Storage:Store at -20℃
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Remarks

BMS-863233, also known as XL-413, is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. CDC7 kinase inhibitor BMS-863233 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA replication and mitosis, the induction of tumor cell apoptosis, and the inhibition of tumor cell proliferation in CDC7-overexpressing tumor cells. CDC7, a serine-threonine kinase overexpressed in a variety of tumor cell types, plays an essential role in the initiation of DNA replication by activating origins of replication.


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