Polymyxin B Sulfate

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Chemical Information

Product name：Polymyxin B Sulfate	Purity：98% min
CAS NO：1405-20-5	Solubility：H2O : ≥ 25 mg/mL
Molecular Formula：C₅₆H₁₀₀N₁₆O₁₇S	Package：Package according to customer requirements
Molecular Weight：1301.56	Storage：Store at 2-8ºC

Quality control

COA

Remarks

Antibiotic with bactericidal action on E. coli. Binds to the lipid A portion of bacterial lipopolysaccharides. Induces pore formation in the membranes of cortex cells from excised sorghum roots. Mixture of Polymyxin B1 and B2 sulfate. Biological potency (dry basis): >6000U/mg.

Properties:
Appearance & Physical State: White crystalline powder
Boiling Point: 1651ºC at 760 mmHg
Flash Point: 952.3ºC
Vapor Pressure: 0mmHg at 25°C

Antibiotics chemical Related Products:

Doripenem Hydrate; Meropenem; Linezolid; Cefoselis Sulfate; Tebipenem; Tebipenem pivoxil; Amphotericin B; Aztreonam; Cefaclor; Tobramycin; Roxithromycin; Enrofloxacin; Nadifloxacin; Gamithromycin; Orbifloxacin; Kanamycin; Tildipirosin; Ertapenem Sodium; Faropenem sodium ; Ceftizoxime

References

[1]. Rolin O et al. Enzymatic modification of lipid A by ArnT protects Bordetella bronchiseptica against cationic peptides and is required for transmission. Infect Immun. 2014 Feb;82(2):491-9.

[2]. Pye CC et al. Evaluation of biofilm production by Pseudomonas aeruginosa from canine ears and the impact of biofilm on antimicrobial susceptibility in vitro. Vet Dermatol. 2013 Aug;24(4):446-9