Ertapenem Sodium is the sodium salt of ertapenem, a 1-beta-methyl carbapenem and a broad-spectrum beta-lactam antibiotic with bactericidal activity. Ertapenem binds to penicillin binding proteins located on the bacterial cell wall, in particular PBPs 2 and 3, thereby inhibiting the final transpeptidation step in the synthesis of peptidoglycan, an essential component of the bacterial cell wall. Inhibition of peptidoglycan synthesis results in weakening and lysis of the cell wall and cell death. Erapenem is resistant to hydrolysis by a variety of beta-lactamases, including penicillinases, cephalosporinases and extended-spectrum beta-lactamases.
Properties:
Appearance & Physical State: White or off-white powder
Boiling Point: 813.9ºC at 760 mmHg
Flash Point: 446ºC
Vapor Pressure: 5.26E-28mmHg at 25°C
Antibiotics chemical Related Products:
Doripenem Hydrate; Meropenem; Linezolid; Cefoselis Sulfate; Tebipenem; Tebipenem pivoxil; Amphotericin B; Aztreonam; Cefaclor; Tobramycin; Roxithromycin; Enrofloxacin; Nadifloxacin; Gamithromycin; Orbifloxacin; Polymyxin B Sulfate; Kanamycin; Tildipirosin; Faropenem sodium; Ceftizoxime