Linezolid

Linezolid is a synthetic oxazolidinone antibiotic active against a wide range of Gram-positive bacteria, including resistant strains of several species, such as MRSA and penicillin-resistant pneumococci. Linezolid inhibits protein synthesis by binding to domain V of the 23S ribosomal RNA of the 50S subunit of bacterial ribosomes.

Properties:
Appearance & Physical State: White Solid
Density: 1.302 g/cm3
Melting Point: 176-178ºC
Boiling Point: 585.5ºC at 760 mmHg
Flash Point: 307.9ºC
Refractive Index: 1.553
Storage Condition: Store in original container in a cool dark place.
Vapor Pressure: 1.08E-13mmHg at 25°C

Antibiotics chemical Related Products:

Doripenem Hydrate; Meropenem; Cefoselis Sulfate; Tebipenem; Tebipenem pivoxil; Amphotericin B; Aztreonam; Cefaclor; Tobramycin; Roxithromycin; Enrofloxacin; Nadifloxacin; Gamithromycin; Orbifloxacin; Polymyxin B Sulfate; Kanamycin; Tildipirosin; Ertapenem Sodium; Faropenem sodium; Ceftizoxime

[1]. Clemett D, Markham A. Linezolid. Drugs. 2000 Apr;59(4):815-27; discussion 828.

[2]. Chiappini E, Conti C, Galli L et al. Clinical efficacy and tolerability of linezolid in pediatric patients: a systematic review. Clin Ther. 2010 Jan;32(1):66-88.

[3]. Perry CM, Jarvis B. Linezolid: a review of its use in the management of serious gram-positive infections. Drugs. 2001;61(4):525-51.