Tebipenem

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Chemical Information

Product name：Tebipenem	Purity：98% min
CAS NO：161715-21-5	Solubility：DMSO : ≥ 45 mg/mL (117.34 mM)
Molecular Formula：C₁₆H₂₁N₃O₄S₂	Package：Package according to customer requirements.
Molecular Weight：383.486	Storage：Store at -20℃

Quality control

COA

Remarks

Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa.

Synonyms:

(1R,5S,6S)-6-(1(R)-Hydroxyethyl)-1-methyl-2-(1-(2-thiazolin-2-yl)azetidin-3-ylsulfanyl)-1-carba-2-penem-3-carboxylic acid;

1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid,3-((1-(4,5-dihydro-2-thiazolyl)-3-azetidinyl)thio)-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-,(4R,5S,6S);

Chemical Properties:

Boiling point: 624.5±65.0 °C(Predicted)

density: 1.75

pka: 4.29±0.60(Predicted)

Antibiotics chemical Related Products:

Doripenem Hydrate; Meropenem; Linezolid; Cefoselis Sulfate; Tebipenem pivoxil; Amphotericin B; Aztreonam; Cefaclor; Tobramycin; Roxithromycin; Enrofloxacin; Nadifloxacin; Gamithromycin; Orbifloxacin; Polymyxin B Sulfate; Kanamycin; Tildipirosin; Ertapenem Sodium; Faropenem sodium ; Ceftizoxime

References

[1]. Hazra S, et al. Tebipenem, a new carbapenem antibiotic, is a slow substrate that inhibits the β-lactamase from Mycobacterium tuberculosis. Biochemistry. 2014 Jun 10;53(22):3671-8.

[2]. Seenama C, et al. In vitro activity of tebipenem against Burkholderia pseudomallei. Int J Antimicrob Agents. 2013 Oct;42(4):375.

[3]. Li H, et al. In vitro antibacterial activities of two novel oral antibiotics, tebipenem and cefditoren, and other comparators against community-acquired respiratory tract infection-associated bacterial pathogens: A multicentre study in China. Int J Antimicrob Agents. 2014 Jan;43(1):92-3.