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LY2157299 Galunisertib

LY2157299 Galunisertib 700874-72-2
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Chemical Information
Product name:LY2157299 Galunisertib Purity:98% min
CAS NO:700874-72-2 Solubility:DMSO : ≥ 47 mg/mL (127.23 mM)
Molecular Formula:C22H19N5O Package:Package according to customer requirements
Molecular Weight:369.41916 Storage:Store at -20℃
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Galunisertib, also known as LY2157299, is a novel selective small molecule transforming growth factor beta receptor (TGF-βR) kinase inhibitor. LY2157299 inhibited HCC cell migration on Laminin-5, Fibronectin, Vitronectin, Fibrinogen and Collagen-I and de novo phosphorylation of pSMAD2. LY2157299 inhibited HCC migration and cell growth independently of the expression levels of TGF-βRII.
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