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Luminespib (NVP-AUY922)

Luminespib (NVP-AUY922) 747412-49-3
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Chemical Information
Product name:Luminespib (NVP-AUY922) Purity:98% min
CAS NO:747412-49-3 Solubility:DMSO: ≥ 62 mg/mL
Molecular Formula:C26H31N3O5 Package:Package according to customer requirements
Molecular Weight:465.541 Storage:Store at -20℃
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Remarks

Luminespib, also known as AUY-922 (or NVP-AUY922), is a derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins; the inhibition of cell proliferation; and the elevation of heat shock protein 72 (Hsp72) in a wide range of human tumor cell lines.

 

Properties:

Density: 1.234 g/cm3

Boiling Point: 640.1ºC at 760 mmHg

Flash Point: 340.9ºC

Refractive Index: 1.597

 

 

 

HSP (HSP90) inhibitor Related Prodcuts:

Tanespimycin; Alvespimycin; Ganetespib; BIIB021; Onalespib; NVP-BEP800; SNX-2112; PF-04929113; KW-2478; XL888; Zelavespib (PU-H71); KRIBB11; VER-50589; Triptolide; NVP-HSP990; Dimethylenastron; Geldanamycin

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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