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NVP-BEP800

NVP-BEP800 847559-80-2
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Chemical Information
Product name:NVP-BEP800 Purity:98% min
CAS NO:847559-80-2 Solubility: DMSO: 6.2 mg/mL (Need ultrasonic)
Molecular Formula:C21H23Cl2N5O2S Package:Package according to customer requirements
Molecular Weight:480.411 Storage:Store at -20℃
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Remarks

NVP-BEP800, also known as BEP-800, is a novel, fully synthetic, orally bioavailable inhibitor that binds to the NH(2)-terminal ATP-binding pocket of Hsp90. NVP-BEP800 showed activity against a panel of human tumor cell lines and primary human xenografts in vitro at nanomolar concentrations. In A375 melanoma and BT-474 breast cancer cell lines, NVP-BEP800 induced client protein degradation (including ErbB2, B-Raf(V600E), Raf-1, and Akt) and Hsp70 induction.

 

 

 

HSP (HSP90) inhibitor Related Prodcuts:

Tanespimycin; Luminespib; Alvespimycin; Ganetespib; BIIB021; Onalespib; SNX-2112; PF-04929113; KW-2478; XL888; Zelavespib (PU-H71); KRIBB11; VER-50589; Triptolide; NVP-HSP990; Dimethylenastron; Geldanamycin

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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