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Dimethylenastron

Dimethylenastron 863774-58-7
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Chemical Information
Product name:Dimethylenastron Purity:98% min
CAS NO:863774-58-7 Solubility:DMSO : ≥ 31 mg/mL (102.52 mM)
Molecular Formula:C16H18N2O2S Package:Package according to customer requirements
Molecular Weight:302.391 Storage:Store at -20℃
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Remarks

Dimethylenastron is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM). Dimethylenastron suppresses human pancreatic cancer cell migration and invasion in vitro via allosteric inhibition of mitotic kinesin Eg5. The inhibition of kinesin Eg5 by small molecules such as monastrol is currently evaluated as an approach to develop a novel class of antiproliferative drugs for the treatment of malignant tumours.

 

 

 

 

HSP (HSP90) inhibitor Related Prodcuts:

Tanespimycin; Luminespib; Alvespimycin; Ganetespib; BIIB021; Onalespib; NVP-BEP800; SNX-2112; PF-04929113; KW-2478; XL888; Zelavespib (PU-H71); KRIBB11; VER-50589; Triptolide; NVP-HSP990; Geldanamycin

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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