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PF-04929113 SNX-5422

PF-04929113 SNX-5422 908115-27-5
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Chemical Information
Product name:PF-04929113 SNX-5422 Purity:98% min
CAS NO:908115-27-5 Solubility: 10 mM in DMSO
Molecular Formula:C25H30F3N5O4 Package:Package according to customer requirements
Molecular Weight:521.532 Storage:Store at -20℃
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Remarks

PF-04929113, also known as SNX-5422; is a synthetic prodrug targeting the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. Although the mechanism of action remains to be fully elucidated, Hsp90 inhibitor SNX-5542 is rapidly converted to SNX-2112, which accumulates in tumors relative to normal tissues. SNX-2112 inhibits Hsp90, which may result in the proteasomal degradation of oncogenic client proteins, including HER2/ERBB2, and the inhibition of tumor cell proliferation.

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